| 专利名称 | Substituted 1-hydroxy-pyridin-2(1H)-ones, and methods of making and using same | ||
| 申请号 | US16204748 | 申请日 | |
| 公开（公告）号 | US10550084B2 | 公开（公告）日 | |
| 申请（专利权）人 | Arbutus Biopharma Corporation | 发明人 | Ramesh Kakarla; Bruce D Dorsey |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
The present invention includes novel substituted 1-hydroxy-pyridin-2(1H)-ones, which can be used to treat or prevent hepatitis B virus (HBV) infections in a patient. In certain embodiments, the compounds and compositions of the invention inhibit HBV RNAse H activity. |
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