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专利概况
专利名称 Single-cycle virus for the development of canine influenza vaccines
申请号 US15753688 申请日
公开(公告)号 US10548966B2 公开(公告)日
申请(专利权)人 UNIVERSITY OF ROCHESTER; CORNELL UNIVERSITY 发明人 Luis Martinez Sobrido; Aitor Nogales Gonzalez; Colin Parrish
专利来源 国家知识产权局 转化方式
摘要

The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon the discovery that one or more mutations in segment 4 of the viral genome produces a single cycle infectious CIV (sciCIV). The sciCIV does not allow for the production of infectious progeny, but is able to induce a CIV-specific immune response.

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