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专利概况
专利名称 Muscarinic agonists
申请号 US15749743 申请日
公开(公告)号 US10548884B2 公开(公告)日
申请(专利权)人 Heptares Therapeutics Limited 发明人 Giles Albert Brown; Miles Stuart Congreve; Mark Pickworth; Mark David Rackham; Benjamin Gerald Tehan
专利来源 国家知识产权局 转化方式
摘要

This invention relates to compounds that are agonists of the muscarinic M4 receptor and/or M4 receptor and which are useful in the treatment of muscarinic M1/M4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds include those according to formula 1a or a salt thereof, wherein n, p, Q, R1, R2, R3, R9 and R4 are as defined herein.

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