| 专利名称 | Alogliptin formulation | ||
| 申请号 | US15736592 | 申请日 | |
| 公开(公告)号 | US10548848B2 | 公开(公告)日 | |
| 申请(专利权)人 | Hexal AG | 发明人 | Thomas Kohr; Christian Wawra; Marco Marchesan |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
The present invention belongs to the field of pharmaceutical industry and relates to a pharmaceutical composition comprising an intragranulate phase and an extragranulate phase, wherein the pharmaceutically active ingredient (API) 2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2, 4-dioxo-3, 4-dihydropyrimidin-1(2H)-yl}methyl)benzonitrile or a pharmaceutically acceptable salt thereof, is present in the intragranulate phase, wherein said intragranulate phase is free from microcrystalline cellulose. Further, the present invention relates to a process for preparing the same. |
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