专利名称 | USE OF OCTAKETIDE SYNTHASES TO PRODUCE KERMESIC ACID AND FLAVOKERMESIC ACID | ||
申请号 | US16506256 | 申请日 | |
公开(公告)号 | US20200040367A1 | 公开(公告)日 | |
申请(专利权)人 | Danmarks Tekniske Universitet; K鴅enhavns Universitet | 发明人 | Birger Lindberg M鴏ler; Bj鴕n Madsen; Dan St鎟k; Finn Thyge Okkels; Johan Andersen Ranberg; Kenneth Thermann Kongstad; Kim Binderup; Mads Bennedsen; Majse Nafisi; Paiman Khorsand Jamal; Rubini Maya Kannangara; Uffe Hasbro Mortensen; Ulf Thrane; Rasmus John Normand Frandsen |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
A method for producing an octaketide derived aromatic compound of interest (e.g. carminic acid), wherein the method comprises (I) : heterologous expression of a recombinantly introduced Type III polyketide synthase (PKS) gene encoding an octaketide synthase (OKS) to obtain non-reduced octaketide in vivo within the recombinant host cell and (II) : converting in vivo the non-reduced octaketide of step (I) into a C14-C34 aromatic compound of interest (e.g. carminic acid). |
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