Disclosed is a brewing method for radix notoginseng red rice yeast vinegar. A herbal medicine ferment prepared with radix notoginseng as a main raw material is fermented together with the red rice yeast and agaricus bisporus pulp to prepare the brewed vinegar. The herbal medicine ferment is used as a saccharification fermentation agent, and after a long-time brewing process, some red rice yeast is added, wherein the red rice yeast pigment and the red rice yeast polysaccharide can be more sufficiently dissolved in the alcohol and vinegar liquid. The brewed radix notoginseng red rice yeast vinegar product combines the medical efficacies of both radix notoginseng and red rice yeast, has, if being drunk for a long time, significant curative effect for cardiovascular and cerebrovascular diseases. In addition to flavoring, nutritional and healthcare functions of ordinary table vinegars, the radix notoginseng red rice yeast vinegar further has significant auxiliary treatment effect for cardiovascular and cerebrovascular diseases, and compared with traditional Chinese medicine and western medicine special for the treatment of cardiovascular and cerebrovascular diseases, has no toxicity and side effect, and causes no dependence.