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专利概况
专利名称 BINDING MOLECULES FOR BCMA AND CD3
申请号 EP19196304 申请日
公开(公告)号 EP3611193A1 公开(公告)日
申请(专利权)人 Amgen Research (Munich) GmbH; Amgen Inc 发明人 KUFER Peter; RAUM Tobias; HOFFMANN Patrick; KISCHEL Roman; LUTTERBUESE Ralf; RAU Doris; ADAM Paul; BORGES Eric; HEBEIS Barbara; HIPP Susanne
专利来源 国家知识产权局 转化方式
摘要

The present invention relates to a binding molecule which is at least bispecific comprising a first and a second binding domain, wherein the first binding domain is capable of binding to epitope cluster 3 of BCMA, and the second binding domain is capable of binding to the T cell CD3 receptor complex. Moreover, the invention provides a nucleic acid sequence encoding the binding molecule, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention provides a process for the production of the binding molecule of the invention, a medical use of said binding molecule and a kit comprising said binding molecule.

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