| 专利名称 | ANTISENSE OLIGONUCLEOTIDES TARGETING STAT1 | ||
| 申请号 | WOEP19067795 | 申请日 | |
| 公开（公告）号 | WO2020007889A1 | 公开（公告）日 | |
| 申请（专利权）人 | ROCHE INNOVATION CENTER COPENHAGEN A/S | 发明人 | LINDHOLM Eva Marie; SCHMIDT Steffen |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
The present invention relates to antisense LNA oligonucleotides (oligomers) complementary to STAT1 pre-mRNA exon sequences, which are capable of inhibiting the expression of STAT1 protein. Inhibition of STAT1 expression is beneficial for a range of medical disorders including cancer, ischemic stroke and fibrosis such as pulmonary fibrosis or drug-induced fibrosis. |
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