Disclosed is a highly active probiotic solid beverage having resistance to Helicobacter pylori, comprising the following in parts by weight : 40-60 parts of resistant dextrin, 5-15 parts of inulin, 5-15 parts of fructo-oligose, 2-8 parts of Lactobacillus helveticus powder, 2-8 parts of Lactobacillus rhamnosus powder, 2-8 parts of Bifidobacterium animalis powder, 2-8 parts of Bifidobacterium lactis powder, 2-8 parts of Lactobacillus acidophilus powder, and 2-8 parts of Bifidobacterium bifidum powder. Each component of the highly active probiotic solid beverage provided interacts, can promote gastrointestinal motility, improve balance of gastrointestinal flora, and enhance the effect of the single action of each component, and thus can better eliminate Helicobacter pylori and increase the content of beneficial bacteria.