| 专利名称 | COMPOUND FOR TARGETED DEGRADATION OF FAK PROTEIN AND USE THEREOF | ||
| 申请号 | WOCN18094594 | 申请日 | |
| 公开(公告)号 | WO2020006724A1 | 公开(公告)日 | |
| 申请(专利权)人 | TSINGHUA UNIVERSITY | 发明人 | RAO Yu; ZHOU Guangbiao; SUN Yonghui; WU Yue; GAO Hongying |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
Disclosed is a compound, which is a compound of formula I or a stereoisomer, a geometric isomer, a tautomer, a nitrogen oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof : X-Y-Z Formula I, wherein X represents the ligand of the FAK protein, Z represents the ligand of E3 ligase, and Y represents the linker linking X and Z. |
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