专利名称 | 3, 4 - [...] derivatives, and its manufacturing method and applications | ||
申请号 | JP2019523621 | 申请日 | |
公开(公告)号 | JP2020500177A | 公开(公告)日 | |
申请(专利权)人 | JIANGSU HENGRUI MEDICINE CO LTD; SHANGHAI HENGRUI PHARMACEUTICAL CO LTD | 发明人 | ヤン、ファンロン; ジャン、リン; シェン、グアンユエン; フア、フォン; タオ、ウェイカン |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
The present invention relates to a 3, 4-bipyridyl pyrazole derivative, and a preparation method therefor and a medical application thereof. Specifically, the present invention relates to a new 3, 4-bipyridyl pyrazole derivative as shown in formula (I), a preparation method for the derivative, a pharmaceutical composition containing the derivative, a use of the derivative as a therapeutic agent, in particular as a TGF-β inhibitor, and a use of the derivative in the preparation of a drug which treats, prevents or reduces cancer mediated by TGF-β overexpression. The substituents in formula (I) have the same definitions as in the description. |
主管部门:海南中小企业服务 | 建设单位:海南商业联合会
版权所有:海南商业联合会 | 备案号:粤ICP备13083911号(ICP加挂服务)@2017