专利名称 | METHOD OF PRODUCING ANGIOPROTECTIVE AND NOOTROPIC AGENTS | ||
申请号 | RU2018137653 | 申请日 | |
公开(公告)号 | RU2710716C1 | 公开(公告)日 | |
申请(专利权)人 | GENERALOV VASILIJ OLEGOVICH | 发明人 | GENERALOV VASILIJ OLEGOVICH |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
FIELD : biotechnology.SUBSTANCE : invention refers to biotechnology and medicine, namely to producing an angioprotective and nootropic agent in the form of a solid dosage form for oral administration. Method involves separate granulation of 150–600?mg of troxerutin and 5–10?mg of vinpocetine by mixing each of them with a filler selected from polyethylene glycol-6000, sorbitol or mixtures thereof, until homogeneous, mixing with 1–5?% binder solution, selected from sodium salt of carboxymethyl starch, polyethylene oxide, followed by drying in a fluidised bed at temperature of 100?°C, after which the obtained granules are powdered with at least one antifriction agent, such as aerosil, tween-80, magnesium stearate, and pressed to obtain a solid dosage form.EFFECT : invention widens the range of equipment.3 cl, 2 tbl, 4 ex |
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