| 专利名称 | CRYSTALS | ||
| 申请号 | EP17186415 | 申请日 | |
| 公开(公告)号 | EP3275871B1 | 公开(公告)日 | |
| 申请(专利权)人 | Nippon Shinyaku Co Ltd | 发明人 | ITOU Hideyuki |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
[Problem] A main object of the present invention is to provide a novel crystal of 2-{4-[N-(5, 6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}-N-(methylsulfonyl)acetamide (hereinafter referred to as "compound A"). [Means for Resolution] A Form-I crystal of compound A, showing diffraction peaks at 9.4 degrees, 9.8 degrees, 17.2 degrees and 19.4 degrees in the powder X-ray diffraction spectrum thereof. A Form-II crystal of compound A, showing diffraction peaks at 9.0 degrees, 12.9 degrees, 20.7 degrees and 22.6 degrees in the powder X-ray diffraction spectrum thereof. A Form-III crystal of compound A, showing diffraction peaks at 9.3 degrees, 9.7 degrees, 16.8 degrees, 20.6 degrees and 23.5 degrees in the powder X-ray diffraction spectrum thereof. |
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