您好,欢迎来到海南中小企业大数据中心及公共服务平台!     请登录   免费注册
专利概况
专利名称 NOVEL BENZIMIDAZOLONE COMPOUND AND PHARMACEUTICAL USE THEREOF
申请号 EP18768087 申请日
公开(公告)号 EP3597640A1 公开(公告)日
申请(专利权)人 Sumitomo Dainippon Pharma Co Ltd 发明人 MIZUSHIMA Shingo; WATANABE Masaki; IWAMOTO Kohei; URASHIMA Kuniko
专利来源 国家知识产权局 转化方式
摘要

The present invention relates to a medicament for treating or preventing a disease involving Nav 1.7, specifically such neuropathic pain, nociceptive pain, inflammatory pain, small-fiber neuropathy, erythromelalgia, paroxysmal extreme pain disorder, dysuria, and multiple sclerosis, comprising a compound of formula (I) wherein R1a, R1b, R1c, and R1d are hydrogen, halogen, cyano, C1-4 alkyl, C1-4 alkoxy, etc., provided that at least one of R1a, R1b, R1c and R1d is the above C6-10 aryl, C6-10 aryloxy, etc., R2 and R3 are hydrogen, C1-6 alkyl, C3-10 cycloalkyl, etc., R4 is hydrogen, C1-6 alkyl, C3-4cycloalkyl, etc., m is 0, 1, 2, or 3, L is CR7R8, R7 and R8 are hydrogen, hydroxy group, C1-4 alkyl, C1-4 alkoxy, etc., or a pharmaceutically acceptable salt thereof.

参与列表

主管部门:海南中小企业服务 | 建设单位:海南商业联合会

版权所有:海南商业联合会 | 备案号:粤ICP备13083911号(ICP加挂服务)@2017