| 专利名称 | FUSED PYRIMIDINES AS ISOFORM SELECTIVE PHOSPHOINOSITIDE-3-KINASE-ALPHA INHIBITORS AND PROCESS FOR PREPARATION THEREOF | ||
| 申请号 | US15774520 | 申请日 | |
| 公开(公告)号 | US20200031845A1 | 公开(公告)日 | |
| 申请(专利权)人 | Council of Scientific and Industrial Research | 发明人 | Sandip Bibishan BHARATE; Shashi BHUSHAN; Shabber MOHAMMED; Santosh Kumar GURU; Sonali Sandip BHARATE; Vikas KUMAR; Girish MAHAJAN; Mubashir Javed MINTOO; Dilip Manikrao MONDHE; Ram VISHWAKARMA |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
The present invention relates to fused pyrimidines of formulae I and II wherein, R1, R2 are as herein described. The present invention particularly relates to isoform selective PI3Kα inhibition and their medicinal use as anticancer agents. |
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