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专利概况
专利名称 BINDING MOLECULES FOR BCMA AND CD3
申请号 PL128054 申请日
公开(公告)号 PL2780375T3 公开(公告)日
申请(专利权)人 AMGEN RES MUNICH GMBH; AMGEN INC 发明人 KUFER PETER; RAUM TOBIAS; HOFFMANN PATRICK; KISCHEL ROMAN; LUTTERBUESE RALF; RAU DORIS; ADAM PAUL; BORGES ERIC; HEBEIS BARBARA; HIPP SUSANNE
专利来源 国家知识产权局 转化方式
摘要

The present invention relates to a binding molecule which is at least bispecific comprising a first and a second binding domain, wherein the first binding domain is capable of binding to epitope cluster 3 of BCMA, and the second binding domain is capable of binding to the T cell CD3 receptor complex. Moreover, the invention provides a nucleic acid sequence encoding the binding molecule, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention provides a process for the production of the binding molecule of the invention, a medical use of said binding molecule and a kit comprising said binding molecule.

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