| 专利名称 | BINDING MOLECULES FOR BCMA AND CD3 | ||
| 申请号 | PL128054 | 申请日 | |
| 公开(公告)号 | PL2780375T3 | 公开(公告)日 | |
| 申请(专利权)人 | AMGEN RES MUNICH GMBH; AMGEN INC | 发明人 | KUFER PETER; RAUM TOBIAS; HOFFMANN PATRICK; KISCHEL ROMAN; LUTTERBUESE RALF; RAU DORIS; ADAM PAUL; BORGES ERIC; HEBEIS BARBARA; HIPP SUSANNE |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
The present invention relates to a binding molecule which is at least bispecific comprising a first and a second binding domain, wherein the first binding domain is capable of binding to epitope cluster 3 of BCMA, and the second binding domain is capable of binding to the T cell CD3 receptor complex. Moreover, the invention provides a nucleic acid sequence encoding the binding molecule, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention provides a process for the production of the binding molecule of the invention, a medical use of said binding molecule and a kit comprising said binding molecule. |
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