专利名称 | Mycobacterium tuberculosis H37RV proliferation inhibitor based on (?ethane-1, 2-diol-O, O' )-bis{[N-(2, 3-dimethylphenyl)-2-(oxy-3-methoxybenzylidene)hydrazinecarbothioamido(1-)]aquacopper(II)} nitrate | ||
申请号 | MD20180084 | 申请日 | |
公开(公告)号 | MD4671B1 | 公开(公告)日 | |
申请(专利权)人 | UNIV DE STAT DIN MOLDOVA | 发明人 | GULEA AURELIAN; CRUDU VALERIU; ŢAPCOV VICTOR |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
The invention relates to chemistry and medicine, namely to a biologically active coordination compound of copper from the class of transition metal thiosemicarbazonates. This complex inhibits the mycobacterium tuberculosis H37RV proliferation processes and can be used in medicine for the prevention and treatment of tuberculosis.According to the invention, claimed is (?ethane-1, 2-diol-O, O' )-bis{[N-(2, 3-dimethylphenyl)-2-(oxy-3-methoxybenzylidene)hydrazinecarbothioamido(1-)]aquacopper(II)} nitrate compound of the formula : , which inhibits the mycobacterium tuberculosis H37RV proliferation processes.The compound expands the arsenal of Mycobacterium tuberculosis proliferation inhibitors with high biological activity. |
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