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专利概况
专利名称 New compounds having PPAR-γ activity, and medical use thereof
申请号 KR1020180108871 申请日
公开(公告)号 KR102072378B1 公开(公告)日
申请(专利权)人 부산대학교 산학협력단 发明人 정지형; 주쥐란
专利来源 国家知识产权局 转化方式
摘要

The present invention PPAR- γ relates to a novel compound having activity and a medical, use thereof, in which the anti-inflammatory avian metabolites can be used in the present invention, as well as anti-inflammatory 15d-PGJ avian metabolites. 2 The (PPAR- γ main structural motifs of Ligolipogo) biLithospermene PPAR- γ is combined to synthesize an aromatic ring enone jasmonate derivative, which acts as a secondary active agent, and is used as, 15d-PGJ an active ingredient. 2 The exoskeleton enone moiety of PPAR- γ is essential for the covalent bond of the cysteine residues of the ligand (Cys285)-binding domain with the cysteine residue of the, ligand-binding domain, as described above. As a PPAR- γ result, it was confirmed that, the compound of the present invention can be useful in the development of a clinically applicable. secondary ligand as a diabetes and anti-inflammatory agent, PPAR- γ as shown in SEQ ID No.2.5.

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