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专利概况
专利名称 Alogliptin formulation
申请号 US15736592 申请日
公开(公告)号 US10548848B2 公开(公告)日
申请(专利权)人 Hexal AG 发明人 Thomas Kohr; Christian Wawra; Marco Marchesan
专利来源 国家知识产权局 转化方式
摘要

The present invention belongs to the field of pharmaceutical industry and relates to a pharmaceutical composition comprising an intragranulate phase and an extragranulate phase, wherein the pharmaceutically active ingredient (API) 2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2, 4-dioxo-3, 4-dihydropyrimidin-1(2H)-yl}methyl)benzonitrile or a pharmaceutically acceptable salt thereof, is present in the intragranulate phase, wherein said intragranulate phase is free from microcrystalline cellulose. Further, the present invention relates to a process for preparing the same.

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