The object of the invention is a composition with domiphen bromide and pharmaceutically acceptable adjuncts, which is claimed to contain (per 100 ml of the solution) : - domiphen bromide in an amount of 0.01-0.10%, preferably 0.01-0.03%; - purified water from 90 to 99.9%; - mineral salts (buffering, responsible for isotonicity), preferably NaCl, KCl, CaCl2, MgCl2, NaH2PO4, KH2PO4, Na2HPO4, K2HPO4, Na2CO3, NaHCO3, in an amount of 0.5 to 5.0%, preferably 0.5 - 1.5%; - optionally aromas, preferably mint, apple, anise, lime, lemon, raspberry, cinnamon, clove in an amount of 0.1 to 0.9%.